Why the study?
Does diabetes mellitus at baseline increase long-term mortality in patients hospitalized with acute myocardial infarction?
Population
337 patients hospitalized with acute myocardial infarction (MI), mean age 66.4 years, 61.1% men.
Comparison
Presence of diabetes mellitus (DM) at baseline vs Absence of diabetes mellitus at baseline
Design
Cohort
Follow-up
median 16.6 years
Key result
Baseline diabetes mellitus was associated with increased long-term all-cause mortality (HR 1.31, P=0.038) and cardiovascular mortality (HR 1.69, P=0.001) in patients following acute MI.
Authors
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Diabetes at acute MI presentation was associated with higher long-term mortality; leaves open whether it merits MI-equivalent status in contemporary cohorts.
Cohort (n=337)
Does diabetes mellitus at baseline increase long-term mortality in patients hospitalized with acute myocardial infarction?
Hazard Ratio: 1.31
p-value: p=0.038
In patients with acute myocardial infarction, diabetes mellitus confers a long-term mortality risk equivalent to having had a previous MI, suggesting DM should be considered an MI equivalent.
Gruppetta et al. (2010) conducted a cohort in Acute Myocardial Infarction (n=337). Diabetes mellitus at baseline vs. No diabetes mellitus was evaluated on Long-term survival (all-cause mortality) (HR 1.31, p=0.038). Baseline diabetes mellitus was associated with increased long-term all-cause mortality (HR 1.31, P=0.038) and cardiovascular mortality (HR 1.69, P=0.001) in patients following acute MI.