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A glucose sensor based on FRET between concanavalin A (ConA)-labeled upconverting phosphor (UCP) nanocrystals and chitosan (CS)-labeled graphene oxide (GO) is presented. Binding of ConA to CS quenches the fluorescence of UCP, which is restored in the presence of glucose, owing to competition between glucose and CS for ConA (see picture).
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Zhang et al. (2011) studied this question.
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