Key result
PRP augmentation during arthroscopic rotator cuff repair decreased postoperative retear rates compared to arthroscopy alone.
Why the study?
Recent clinical trials needed assessment regarding the combination of operative treatment of rotator cuff tears and PRP administration on clinical scores and postoperative retear rates.
Does PRP augmentation improve clinical scores and reduce retear rates in patients undergoing arthroscopic repair of shoulder rotator cuff tears?
Meta-Analysis
Does PRP augmentation improve clinical scores and reduce retear rates in patients undergoing arthroscopic repair of shoulder rotator cuff tears?
PRP augmentation during arthroscopic rotator cuff repair reduces retear rates but its clinical benefit on shoulder pain and function remains inconclusive.
Answers are grounded in this paper and cite their sources.
PRP augmentation may warrant consideration to lower retear risk after rotator cuff repair; confirms structural benefit while leaving clinical scores open.
The aim of this review and meta-analysis is to assess recent clinical trials concerning the combination of operative treatment of rotator cuff tears and the administration of PRP and its effect on clinical scores and postoperative retear rates. The trials were used to compare the combination of PRP treatment and arthroscopic rotator cuff repair to arthroscopy alone. Twenty-five clinical trials were reviewed. A risk-of-bias assessment was made for all randomized clinical trials included, using the Cochrane collaboration’s tool as well as a quality assessment for all non-randomized studies utilizing the Newcastle−Ottawa scale. The PRP-treated patients showed statistically significant improvement postoperatively compared to control groups concerning the Constant−Murley (mean difference 2.46, 95% CI 1.4−3.52, p < 0.00001), SST (mean difference 0.32, 95% CI 0.02−0.63, p = 0.04), and UCLA (mean difference 0.82, 95% CI 0.23−1.43, p = 0.07) scores. A statistically significant decrease of retear rates in the PRP-treated patients, with a risk ratio of 0.78 (95% CI 0.65−0.94, p = 0.01), was found. We believe that the results presented have positive aspects, especially concerning the retear risk, but are yet inconclusive concerning clinical results such as shoulder pain and function.
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Trantos et al. (2023) conducted a meta-analysis in Rotator cuff tears. PRP augmentation of arthroscopic rotator cuff repair vs. Arthroscopy alone was evaluated on Retear rates (RR 0.78, 95% CI 0.65-0.94, p=0.01). PRP augmentation during arthroscopic rotator cuff repair decreased postoperative retear rates compared to arthroscopy alone.
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