Key result
Obesity and excess fat deposition drive metabolic syndrome and chronic inflammation, while perivascular adipose tissue serves a paracrine role regulating vascular function.
Design
Review
Authors
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No immediate practice changes for obesity-related vascular disease; leaves open therapeutic targeting of perivascular adipose tissue.
Perivascular adipose tissue acts as an active paracrine organ regulating vascular function, highlighting its potential role in the cardiovascular complications of obesity and metabolic syndrome.
Achike et al. (2010) conducted a review in Obesity and metabolic syndrome. Obesity and excess fat deposition drive metabolic syndrome and chronic inflammation, while perivascular adipose tissue serves a paracrine role regulating vascular function.
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