Key result
In healthy individuals of African descent, the 95th prediction bands for ambulatory blood pressure at age 38 were ~135/85 mmHg (24h), 140/90 mmHg (daytime), and 130/80 mmHg (night-time).
Why the study?
Reference values for 24 h ambulatory blood pressure monitoring in an African community had not been established.
What are the reference values for 24-hour ambulatory blood pressure in a healthy African community?
Cross-Sectional (n=1,219)
No
What are the reference values for 24-hour ambulatory blood pressure in a healthy African community?
This study establishes preliminary 24-hour ambulatory blood pressure thresholds for diagnosing hypertension in individuals of African descent, demonstrating values similar to other demographics.
May refine ABPM thresholds in African descent adults; extends normative data but leaves open outcome validation.
OBJECTIVE: We aimed to establish reference values for 24 h ambulatory blood pressure (ABP) monitoring in an African community. PATIENTS AND METHODS: We randomly recruited 1219 participants of African ancestry from Soweto, a township in Johannesburg. Twenty-four hour ABP was measured using ABP monitors (model 90207; Spacelab). Complete 24 h ABP measurements from 530 healthy participants with a mean age of 38 were used to determine thresholds. RESULTS: Twenty-four hour, daytime and night-time systolic and diastolic BP increased significantly with age. The 95th prediction bands of this relation at age 38 years were ∼135/85 mmHg for 24 h, 140/90 mmHg for daytime and 130/80 mmHg for night-time ABP values, respectively. These thresholds and absolute ABP values are similar to those observed in individuals of other demographics. These thresholds increase with age by an average of 1.5 mmHg with each decade's increase in age. CONCLUSION: Pending authentication in prospective outcome-based studies, these values might be considered preliminary thresholds to diagnose hypertension in individuals of African descent.
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Bawa-Allah et al. (2019) conducted a cross-sectional in Healthy (n=1,219). 24-hour ambulatory blood pressure monitoring was evaluated on 95th prediction bands for 24-hour, daytime, and night-time ambulatory blood pressure. In healthy individuals of African descent, the 95th prediction bands for ambulatory blood pressure at age 38 were ~135/85 mmHg (24h), 140/90 mmHg (daytime), and 130/80 mmHg (night-time).
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