Demonstrates effective synthesis of P-stereogenic compounds, indicating potential for new chiral ligands.
A palladium‐catalyzed enantioselective CH arylation of N ‐( o ‐bromoaryl)‐diarylphosphinic amides is described for the synthesis of phosphorus compounds bearing a P‐stereogenic center. The method provides good enantioselectivities and high yields. The products were readily transformed into P‐chiral biphenyl monophosphine ligands.
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Lin et al. (2015) studied this question.
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