Key result
In two cases of periocular cutaneous angiosarcoma treated with wide micrographic excision and adjuvant chemoradiotherapy, one patient died from distant metastasis and the other had distant cutaneous recurrences within 1 year.
Case Report (n=2)
Periocular cutaneous angiosarcoma is a rare and aggressive malignancy that can have a much larger extent than clinically apparent and carries a poor prognosis despite aggressive surgical and adjuvant therapy.
Eyelid angiosarcoma may extend beyond apparent margins; adds to sparse case reports but leaves optimal management open.
Angiosarcoma is a rare malignancy with only 8 previous reports of eyelid involvement. The authors report 2 further cases, one as a primary lesion and the other as a recurrence from a contiguous area. In both cases, the lesions appeared relatively inconspicuous, and their extent during micrographic excision was considerably larger than anticipated. Although wide surgical margins were obtained and adjuvant radiotherapy and chemotherapy was undertaken, one patient had died from distant metastasis, while the second had distant cutaneous recurrences within 1 year.
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Wiwatwongwana et al. (2010) conducted a case report in Periocular cutaneous angiosarcoma (n=2). Micrographic excision, adjuvant radiotherapy, and chemotherapy was evaluated on Clinical outcome (metastasis, recurrence, or death). In two cases of periocular cutaneous angiosarcoma treated with wide micrographic excision and adjuvant chemoradiotherapy, one patient died from distant metastasis and the other had distant cutaneous recurrences within 1 year.
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