Key result
PDE11A holds promise as a therapeutic target due to its restricted tissue expression, distinct splice variants, and the apparent safety observed in PDE11A knockout mice.
PDE11A holds promise as a future therapeutic target due to its restricted tissue expression, distinct splice variants, and the apparent safety of its knockout in mice.
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May support PDE11A as a drug target; leaves open confirmation of safety and efficacy in humans.
Michy P. Kelly (2014) reported a review. PDE11A targeted therapies was evaluated. PDE11A holds promise as a therapeutic target due to its restricted tissue expression, distinct splice variants, and the apparent safety observed in PDE11A knockout mice.
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