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Background: Macrophages are crucial in the development and progression of various diseases. To monitor their role, various proteins expressed by macrophages may be used as imaging target. In this preclinical study we investigate the value of the somatostatin receptor subtype 2 (SSTR2) as a novel imaging marker for proinflammatory macrophages, using an experimental osteoarthritis (OA) mouse model.
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Tiel et al. (2020) studied this question.
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