Key result
A novel model of exercise walking training in post-CABG patients did not significantly improve 6-minute walk distance compared to standard rehabilitation, but significantly reduced body mass, fasting glucose, and hsCRP levels.
Why the study?
Does a novel model of exercise walking training based on the 6-min walking test improve exercise capacity, metabolic parameters, and autonomic balance in low-risk men after CABG?
Cohort (n=119)
No
Does a novel model of exercise walking training based on the 6-min walking test improve exercise capacity, metabolic parameters, and autonomic balance in low-risk men after CABG?
Absolute Event Rate: 515% vs 519%
A novel interval walking training program based on the 6-minute walking test is feasible in post-CABG patients and provides additional benefits in body mass control, glycemic control, systemic inflammation, and sympathovagal balance compared to standard cardiac rehabilitation alone.
Enables simple VT-based training prescription via 6-MWT in CR; extends accessible methods for post-CABG patients.
BACKGROUND: Exercise training is an established, guideline-recommended treatment approach in cardiovascular disease. Designing novel methods of exercise training that would be accepted by the patients seems to be a way to increase patient attendance at cardiac rehabilitation (CR). The 6-min walking test (6-MWT) is a simple, safe and objective method to assess exercise capacity. In patients without heart failure, oxygen consumption after 6 min of walking reaches the ventilatory threshold (VT) level. Training up to the VT level is recommended in CR. Theoretical grounds exist for designing a novel model of CR based on diagnostic 6-MWT. AIM: Pilot implementation and evaluation of the effectiveness of a new form of walking training based on 6-MWT in low-risk patients after coronary artery bypass grafting (CABG). METHODS: The study included 119 men after CABG undergoing phase II CR. Depending on whether patients granted a consent to undergo home-based electrocardiography (ECG) telemonitored CR or not, they were divided into two groups: group A (60 patients) - standard CR combined with the new model (walking 6 times for 6 min with 3-min intervals) for 5 days a week; and group B (59 controls) - standard CR. At baseline and after 3 and 12 months, the patients underwent the following tests: 6-MWT, 24-h Holter ECG monitoring (including evaluation of heart rate variability), and biochemical laboratory tests. RESULTS: No significant differences in 6-MWT distance were found between the groups at baseline and at 3 and 12 months. At 3 months, 6-MWT distance increased significantly in both groups (group A: 419 ± 73 vs. 515 ± 70 m, p < 0.02; group B: 422 ± 86 vs. 519 ± 73 m, p < 0.02). At 3 and 12 months, body mass was higher in group B controls (p < 0.05). At 3 months, glycaemia and high-sensitivity C-reactive protein (hsCRP) levels were significantly lower in group A patients (p < 0.05). At 12 months, triglyceride levels were higher in group B (p < 0.05). At 3 months, SDNN was higher in group A. After 12 months, LF was lower in group A. At baseline, the LF/HF ratio was significantly higher in group A (p < 0.05) but during further follow-up, favourable changes in the LF/HF ratio were noted only in group A. CONCLUSIONS: The novel model of exercise walking training had a favourable effect on body mass, glycaemia and hsCRP level reduction, and induced favourable changes of the sympathovagal balance.
No takes yet. Share an insight, caveat, or question.
Wolszakiewicz et al. (2015) conducted a cohort in Coronary artery bypass grafting (CABG) (n=119). Interval walking training based on 6-MWT vs. Standard cardiac rehabilitation was evaluated on 6-minute walking test (6-MWT) distance at 3 months (meters). A novel model of exercise walking training in post-CABG patients did not significantly improve 6-minute walk distance compared to standard rehabilitation, but significantly reduced body mass, fasting glucose, and hsCRP levels.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: