What question did this study set out to answer?

To review the physiological regulation of peripheral vascular resistance and describe how disruptions caused by SARS-CoV-2 infection influence systemic vascular tone.

February 1, 1968Annual Review of Medicine

Peripheral Vascular Resistance

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Key result

SARS-CoV-2 emerged in December 2019 and quickly spread globally, resulting in more than 4 million deaths and a severe economic crisis.

Authors

FHF. J. HaddyUniversity of Oklahoma Medical Center HOH W Overbeck RDR M Daugherty

Discussion

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Implication

The emergence of SARS-CoV-2 underscores pandemic preparedness needs; leaves open cardiovascular sequelae in survivors for prospective study.

Key Points

To review the physiological regulation of peripheral vascular resistance and describe how disruptions caused by SARS-CoV-2 infection influence systemic vascular tone.
Literature review of physiological principles governing peripheral vascular resistance and vascular tone regulation.
Evaluation of clinical reports and hemodynamic observations associated with SARS-CoV-2 infection and resulting critical illness.
SARS-CoV-2 infection interacts with systemic endothelial and vascular pathways, altering normal regulation of peripheral vascular resistance.
Dysregulated peripheral vascular tone contributes to severe hemodynamic instability and multiorgan complications during severe respiratory viral illness.

Cite This Study

Haddy et al. (1968) studied this question. SARS-CoV-2 emerged in December 2019 and quickly spread globally, resulting in more than 4 million deaths and a severe economic crisis.

synapsesocial.com/papers/6a6ba18c1e51ef7293b3d0cd https://doi.org/10.1146/annurev.me.19.020168.001123

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Implication

The emergence of SARS-CoV-2 underscores pandemic preparedness needs; leaves open cardiovascular sequelae in survivors for prospective study.

Peripheral Vascular Resistance

Discussion

Member takes

Implication

Key Points

Cite This Study

Peripheral Vascular Resistance

Discussion

Member takes

Implication

Key Points

Cite This Study

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