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March 1, 1991Molecular and Cellular BiologyOpen Access

Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.

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Authors

SCSusan R. CordleVanderbilt University Medical CenterEHEva HendersonVanderbilt University Medical CenterHMHoward C. MasuokaIndiana University – Purdue University Indianapolis

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Cite This Study

Cordle et al. (1991) studied this question.

synapsesocial.com/papers/6a6ba2fb050bc01bbbcb7708https://doi.org/10.1128/mcb.11.3.1734
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of a Pancreatic β-Cell Insulin Gene Transcription Factor That Binds to and Appears To Activate Cell-Type-Specific Expression: Its Possible Relationship to Other Cellular Factors That Bind to a Common Insulin Gene Sequence1990 · 93 citations
  2. 2Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene.1990 · 56 citations
  3. 3Guinea pig preproinsulin gene: an evolutionary compromise?1984 · 81 citations
  4. 4INSULIN BIOSYNTHESIS IN THE RAT: DEMONSTRATION OF TWO PROINSULINS1969 · 156 citations
  5. 5Two Distinct Transcription Factors that Bind the Immunoglobulin Enhancer μE5/κE2 Motif1990 · 482 citations