Key result
In 173 cognitively normal adults, higher physical activity was associated with small performance gains on executive functioning and working memory tasks over time in APOE4 carriers.
Why the study?
Does higher physical activity improve trajectories of cognitive functioning in cognitively normal middle-aged and older adults?
Population
173 cognitively normal (Clinical Dementia Rating 0) middle-aged and older adults, mean age 60.7 ± 7.8 years.
Comparison
Higher self-reported physical activity levels vs Lower self-reported physical activity levels
Design
Cohort
Authors
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Physical activity was associated with preserved cognition; leaves open whether increasing it prevents Alzheimer disease.
Cohort (n=173)
Does higher physical activity improve trajectories of cognitive functioning in cognitively normal middle-aged and older adults?
Higher physical activity may provide slight cognitive benefits over time specifically in older adults at genetic risk for Alzheimer disease (APOE4 carriers).
Pizzie et al. (2013) conducted a cohort in Cognitively normal (n=173). Physical activity vs. Lower physical activity was evaluated on Trajectories of cognitive functioning. In 173 cognitively normal adults, higher physical activity was associated with small performance gains on executive functioning and working memory tasks over time in APOE4 carriers.
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