Key result
The 2- to 6-Hz oscillation in sympathetic nerve discharge is generated in the brain stem, as cervical spinal cord transection abolished SND while medullary oscillations remained unchanged.
Population
Baroreceptor-denervated decerebrate cats and urethan-anesthetized rats
Design
Preclinical
Authors
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Does not inform clinical practice; leaves open brainstem generation of sympathetic rhythms in humans.
The 2- to 6-Hz oscillation in sympathetic nerve discharge is generated in the brain stem, as evidenced by persistent medullary oscillations following spinal cord transection in animal models.
Zhong et al. (1993) studied this question. Cervical spinal cord transection vs. Intact spinal cord (baseline) was evaluated on Correlation between 2- to 6-Hz oscillation in medullary population activity and sympathetic nerve discharge. The 2- to 6-Hz oscillation in sympathetic nerve discharge is generated in the brain stem, as cervical spinal cord transection abolished SND while medullary oscillations remained unchanged.
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