Key result
Simulated exercise conditions in an in vitro pulsatile flow rig induced turbulence in the aortic sinus vortex, with the highest turbulent intensities occurring near the sinus ridge.
Population
In vitro pulsatile flow rig modeling the geometry of the natural aortic root
Design
Preclinical
Authors
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In vitro aortic sinus vortex data may refine valve prosthesis design; leaves open in vivo hemodynamic effects.
In vitro modeling demonstrates that the aortic sinus vortex becomes turbulent under simulated exercise conditions, which may explain clinical murmurs and the localization of aortic root pathology.
Jon Peacock (1990) studied Aortic sinus vortex stability. Simulated exercise conditions was evaluated on Stability of the sinus flow. Simulated exercise conditions in an in vitro pulsatile flow rig induced turbulence in the aortic sinus vortex, with the highest turbulent intensities occurring near the sinus ridge.
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