Key result
ACTN3 and COL5A1 polymorphisms were associated with a sports injury risk of OR 0.98 in weightlifters compared to healthy controls.
Why the study?
The high incidence of sports injuries in elite athletes is a concern, and genomics could address injuries by identifying single nucleotide polymorphisms that affect athlete health.
Do ACTN3 and COL5A1 polymorphisms affect the risk of sports injuries in weightlifters?
Meta-Analysis (n=2,069)
Do ACTN3 and COL5A1 polymorphisms affect the risk of sports injuries in weightlifters?
Odds Ratio: 0.98 (95% CI 0.64–1.5)
p-value: p=0.03
Polymorphisms in the ACTN3 and COL5A1 genes show a statistically significant but highly heterogeneous association with sports injuries in weightlifters, highlighting the need for larger genomic studies in sports medicine.
SNP identification may guide injury prevention in elite athletes; extends genomic meta-analysis to Colombian sports medicine.
The high incidence of sports injuries in elite athletes is a concern in sports medicine, a broad vision of sport injuries in Colombia and its pathophysiology can be achieved in the scope of genomics, which could respond to numerous sports injuries from the Identification of single nucleotide polymorphism that affect the health of athletes and often distance them from the field of play.
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Nancy Janneth Molano Tobar (2020) conducted a meta-analysis in Sports injuries (n=2,069). ACTN3 and COL5A1 polymorphisms vs. Healthy controls was evaluated on Risk of sports injury associated with ACTN3 polymorphism (OR 0.98, 95% CI 0.64-1.50, p=0.03). ACTN3 and COL5A1 polymorphisms were associated with a sports injury risk of OR 0.98 in weightlifters compared to healthy controls.
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