Key result
The ROSE prehabilitation program improved 6-minute walk test distance at 30 days post-surgery compared to standard care (adjusted mean difference 41.7 m; 95% CI 8.7-74.8; p=0.015).
Why the study?
Major abdominal surgery carries a high complication rate and frailty increases adverse surgical risks, but the efficacy of multimodal prehabilitation in mitigating functional decline remained unproven.
Does a multimodal prehabilitation program with supervised exercise improve 6-min walk test distance in frail and pre-frail elderly undergoing major abdominal surgery?
RCT (n=74)
Does a multimodal prehabilitation program with supervised exercise improve 6-min walk test distance in frail and pre-frail elderly undergoing major abdominal surgery?
Mean Difference: 41.7 (95% CI 8.7–74.8)
Absolute Event Rate: 287.6% vs 260.1%
p-value: p=0.015
A multimodal prehabilitation program with supervised exercise improves postoperative functional capacity in frail older adults undergoing major abdominal surgery.
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May reduce functional decline in frail elderly; leaves open confirmation via RCTs before practice change.
Chow et al. (2023) conducted an RCT in Frail and pre-frail elderly undergoing major abdominal surgery (n=74). Multimodal Recovery of Surgery in the Elderly (ROSE) prehabilitation program vs. Standard physiotherapy advice was evaluated on 6-min walk test (6MWT) distance at 30 days follow-up after surgery (MD 41.7, 95% CI 8.7-74.8, p=0.015). The ROSE prehabilitation program improved 6-minute walk test distance at 30 days post-surgery compared to standard care (adjusted mean difference 41.7 m; 95% CI 8.7-74.8; p=0.015).
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