Key result
Platelet physiological functions, including shape change, aggregation, and secretion, are mediated by specific agonists and signal transduction mechanisms essential for haemostasis and thrombosis.
Population
Platelets (basic science review)
Design
Review
Authors
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Platelet activation pathways outlined; leaves open targeted antiplatelet strategies in clinical settings.
This review summarizes the fundamental physiological mechanisms of platelet activation, adhesion, and aggregation critical for haemostasis and thrombosis.
Holm Holmsen (1989) reported a review. Platelet physiological functions, including shape change, aggregation, and secretion, are mediated by specific agonists and signal transduction mechanisms essential for haemostasis and thrombosis.
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