January 1, 1991Journal of Cardiovascular Pharmacology
Clinical Significance of Left Ventricular Hypertrophy
Key result
Echocardiographic left ventricular hypertrophy is more prevalent than ECG-detected hypertrophy (17.4% vs. 2.4%) and is an important predictor of cardiovascular morbidity and mortality.
Why the study?
Does left ventricular hypertrophy detected by ECG or echocardiography predict cardiovascular morbidity and mortality?
Population
Subjects in the Framingham Heart Study
Design
Review
Authors
Discussion
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Member takes
Implication
ECG LVH signals mortality exceeding post-MI; leaves open whether regression improves outcomes in modern cohorts.
Structured PICO
Does left ventricular hypertrophy detected by ECG or echocardiography predict cardiovascular morbidity and mortality?
P
Population
Subjects in the Framingham Heart Study
E
Exposure
Detection of left ventricular hypertrophy (LVH) by electrocardiogram (ECG) or echocardiography
O
Outcome
Cardiovascular disease morbidity and mortalityhard clinical
Main Result
Absolute Event Rate: 17.4% vs 2.4%
Left ventricular hypertrophy, whether detected by ECG or the more sensitive echocardiogram, is a significant predictor of cardiovascular morbidity and mortality.
Limitations
- The extent to which prevention or regression of LVH in response to antihypertensive drug therapy will alter associated risks awaits additional investigation.
Cite This Study
Daniel Levy (1991) conducted a review in Left ventricular hypertrophy. Left ventricular hypertrophy vs. Absence of left ventricular hypertrophy was evaluated on Prevalence of left ventricular hypertrophy (Echocardiographic vs. ECG). Echocardiographic left ventricular hypertrophy is more prevalent than ECG-detected hypertrophy (17.4% vs. 2.4%) and is an important predictor of cardiovascular morbidity and mortality.