Key result
Underweight was significantly associated with an increased prevalence of microalbuminuria in men (OR 13.22) compared to normal weight, whereas abdominal obesity was not significantly associated.
Why the study?
Is body mass index or waist circumference associated with the prevalence of microalbuminuria in adults without diabetes, hypertension, renal failure, or overt proteinuria?
Cross-Sectional (n=3,257)
Is body mass index or waist circumference associated with the prevalence of microalbuminuria in adults without diabetes, hypertension, renal failure, or overt proteinuria?
Odds Ratio: 13.22 (95% CI 2.55–68.63)
p-value: p=0.002
In a healthy Korean population without diabetes or hypertension, being underweight, rather than having abdominal obesity, is independently associated with an increased risk of microalbuminuria in men.
Microalbuminuria associates with underweight but not abdominal obesity in healthy Korean adults; hypothesis-generating and should not yet change screening practice.
BACKGROUND: Microalbuminuria and obesity markers are known risk factors for cardiovascular or renal disease. This study aimed to evaluate the prevalence of microalbuminuria according to body mass index (BMI) and abdominal obesity criteria. METHODS: The study subjects included 3,979 individuals aged 30 years or older who did not have diabetes, hypertension, renal failure, or overt proteinuria, from among those who participated in The Korean National Health and Nutrition Examination Survey in 2013, a cross-sectional, nationally representative, stratified survey. Microalbuminuria was defined as a urinary albumin to creatinine ratio of 30 to 300 mg/g. BMI and waist circumference were classified according to the Asia-Pacific criteria. RESULTS: The prevalence of microalbuminuria was found to be 5.1%. In the normoalbuminuria group, 3.4%, 41.7%, 24%, 27.6%, and 3.2% of participants were included in the underweight, normal, overweight, obesity 1, and obesity 2 groups, respectively. These percentages in the microalbuminuria group were 7.1%, 34.5%, 19.2%, 28.6%, and 10.6%, respectively (P<0.001). The waist circumference in men was 21.4% in the normoalbuminuria group and 36.5% in the microalbuminuria group (P=0.004). Logistic regression analyses were performed to evaluate the relationship between the presence of microalbuminuria and BMI or waist circumference groups. The risk of microalbuminuria was significant only in the underweight group (odds ratio, 13.22; 95% confidence interval, 2.55-68.63; P=0.002) after adjusting for confounding factors, abdominal obesity was not significantly associated with microalbuminuria. CONCLUSION: The prevalence of microalbuminuria in a general population in Korea was associated with underweight in men and was not associated with waist circumference in either men or women.
No takes yet. Share an insight, caveat, or question.
Seo et al. (2016) conducted a cross-sectional in Microalbuminuria (n=3,257). Underweight (BMI < 18.5 kg/m2) vs. Normal weight (18.5 <= BMI < 23.0 kg/m2) was evaluated on Prevalence of microalbuminuria (OR 13.22, 95% CI 2.55-68.63, p=0.002). Underweight was significantly associated with an increased prevalence of microalbuminuria in men (OR 13.22) compared to normal weight, whereas abdominal obesity was not significantly associated.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: