Why the study?
The association between Lp (a) and coronary artery calcification in asymptomatic individuals remained unclear.
Are elevated serum lipoprotein (a) levels associated with coronary artery calcification in asymptomatic adults?
Population
2019 asymptomatic Korean adults who underwent CACS and Lp (a) testing
Comparison
CACS = 0 vs CACS > 0
Design
Single-center observational study
Key result
Elevated serum lipoprotein (a) levels were independently associated with coronary artery calcification in asymptomatic men aged ≥45 years (P < 0.01).
Authors
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Association between Lp(a) and CAC in asymptomatic adults remains hypothesis-generating; prospective studies needed before clinical adoption.
Cross-Sectional (n=2,019)
No
Are elevated serum lipoprotein (a) levels associated with coronary artery calcification in asymptomatic adults?
p-value: p=<.01
Elevated Lp(a) is independently associated with coronary artery calcification in asymptomatic men aged ≥45 years, suggesting it may serve as a marker of coronary atherosclerosis in this demographic.
Chung et al. (2021) conducted a cross-sectional in Asymptomatic adults (n=2,019). Elevated Lipoprotein (a) was evaluated on Coronary artery calcium score (CACS) > 0 (p=<.01). Elevated serum lipoprotein (a) levels were independently associated with coronary artery calcification in asymptomatic men aged ≥45 years (P < 0.01).
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