Key result
Percutaneous closure of atrial septal defect has a lower overall complication rate than surgery, though major complications like device embolization or cardiac erosion can be potentially lethal.
Why the study?
What are the complications associated with transcatheter closure of atrial septal defects and patent foramen ovale?
What are the complications associated with transcatheter closure of atrial septal defects and patent foramen ovale?
While percutaneous ASD/PFO closure has a lower overall complication rate than surgery, clinicians must be vigilant for rare but potentially lethal complications like device embolization and cardiac erosion.
Potentially lethal complications warrant individualized device selection; leaves open need for comparative safety data.
Percutaneous closure of atrial septal defect has replaced surgical closure in most centers. Percutaneous closure of patent foramen ovale is proposed as an alternative to medical therapy in the prevention of recurrent thromboembolic events in stroke patients. The overall complication rate of the percutaneous procedure is lower than the surgical complication rate. However, some of the major complications of device closure are potentially lethal. The complications vary with device type, age, defect morphology and center volume load. The most significant complications are device embolization, vascular complications at the puncture site, thrombus on the device, recurrent thromboembolic events, atrial arrhythmias and cardiac erosion or perforation. Meticulous technique, careful peri- and post-procedural monitoring and adequate device choice could lower the incidence of complications. If they occur, early recognition and treatment are warranted.
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Daniël De Wolf (2009) conducted a review in Atrial septal defect and patent foramen ovale. Percutaneous closure vs. Surgical closure or medical therapy was evaluated on Complications (device embolization, vascular complications, thrombus, recurrent thromboembolic events, atrial arrhythmias, cardiac erosion or perforation). Percutaneous closure of atrial septal defect has a lower overall complication rate than surgery, though major complications like device embolization or cardiac erosion can be potentially lethal.
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