Key result
A stress hyperglycemia ratio > 1.45 was independently associated with an increased risk of major adverse cardiovascular and cerebrovascular events (HR 2.279) compared to a ratio < 1.14 in patients with acute myocardial infarction undergoing percutaneous coronary intervention.
Why the study?
The study aimed to evaluate the prognostic significance of the stress hyperglycemia ratio in acute myocardial infarction patients who underwent percutaneous coronary intervention.
Does higher stress hyperglycemia ratio predict major adverse cardiovascular and cerebrovascular events in acute myocardial infarction patients undergoing PCI?
Population
3,212 consecutive AMI patients who underwent PCI
Comparison
Groups assigned according to SHR tertiles
Follow-up
Median of 36 months
Authors
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SHR may aid post-PCI risk stratification in AMI; leaves open incremental value and requires prospective validation.
Cohort (n=3,212)
No
Does higher stress hyperglycemia ratio predict major adverse cardiovascular and cerebrovascular events in acute myocardial infarction patients undergoing PCI?
Hazard Ratio: 2.279 (95% CI 1.569–3.311)
Absolute Event Rate: 30.96% vs 11.4%
p-value: p=<0.001
Stress hyperglycemia ratio is an independent predictor of long-term major adverse cardiovascular and cerebrovascular events in AMI patients undergoing PCI.
Meng et al. (2025) conducted a cohort in Acute myocardial infarction (n=3,212). Stress hyperglycemia ratio > 1.45 vs. Stress hyperglycemia ratio < 1.14 was evaluated on Composite major adverse cardiovascular and cerebrovascular events (MACCEs) (HR 2.279, 95% CI 1.569-3.311, p=<0.001). A stress hyperglycemia ratio > 1.45 was independently associated with an increased risk of major adverse cardiovascular and cerebrovascular events (HR 2.279) compared to a ratio < 1.14 in patients with acute myocardial infarction undergoing percutaneous coronary intervention.
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