Among 12 patients with pulmonary artery sarcoma undergoing surgery, 5 died within 3 to 23 months, while the longest survival of 40 and 68 months was observed in patients with leiomyosarcoma.
Case Report (n=12)
Pulmonary artery sarcoma is a rare tumor with poor prognosis, though survival may vary by histologic subtype.
We report 12 cases of pulmonary artery sarcoma. The mean age at diagnosis was 48.4 years. Based on histomorphologic features and immunohistochemical findings, 2 tumors were classified as rhabdomyosarcoma, 4 as leiomyosarcoma, 1 as osteogenic sarcoma, 1 as angiosarcoma, and 4 as high-grade sarcoma. All patients underwent surgery. In addition, 7 patients received neoadjuvant or adjuvant therapy. Five patients died 3 to 23 months after surgery. Three patients were still alive at 8, 27, and 68 months at last follow-up. Another 3 patients were alive at 2, 15, and 40 months and then lost to follow-up. The 2 patients with the longest survival (40 months and 68 months) had a diagnosis of leiomyosarcoma. Both patients with rhabdomyosarcoma died at 3 months after surgery. Pulmonary artery sarcoma is an uncommon entity with a poor prognosis. The role of early diagnosis, histologic classification, surgical treatment, and adjuvant therapy in patient outcome is discussed.
Huo et al. (Wed,) conducted a case report in Pulmonary artery sarcoma (n=12). Surgery was evaluated on Survival. Among 12 patients with pulmonary artery sarcoma undergoing surgery, 5 died within 3 to 23 months, while the longest survival of 40 and 68 months was observed in patients with leiomyosarcoma.