Key result
Following cavo-tricuspid isthmus ablation, recurrent AF occurred in 27% of patients with prior atrial flutter alone compared to 61% of those with both prior atrial flutter and AF (P<0.001).
Why the study?
Does cavo-tricuspid isthmus ablation prevent atrial fibrillation recurrence in patients with atrial flutter alone versus those with combined atrial flutter and atrial fibrillation?
Cohort (n=141)
Does cavo-tricuspid isthmus ablation prevent atrial fibrillation recurrence in patients with atrial flutter alone versus those with combined atrial flutter and atrial fibrillation?
Absolute Event Rate: 27% vs 61%
p-value: p=< 0.001
Cavo-tricuspid isthmus ablation is curative in over 70% of patients with isolated atrial flutter, but frequently fails to prevent AF in patients with a history of both arrhythmias.
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CTI ablation may cure isolated flutter long-term; leaves open AF prevention when flutter coexists with documented AF.
Delise et al. (2006) conducted a cohort in Atrial flutter alone or combined with atrial fibrillation (n=141). Atrial flutter alone prior to ablation vs. Atrial flutter and AF prior to ablation was evaluated on Documented recurrent AF (p=< 0.001). Following cavo-tricuspid isthmus ablation, recurrent AF occurred in 27% of patients with prior atrial flutter alone compared to 61% of those with both prior atrial flutter and AF (P<0.001).
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