Key result
Right frontal acute infarcts were an independent predictor of poststroke anxiety symptoms.
Why the study?
Are right frontal acute infarcts associated with the development of poststroke anxiety symptoms in stroke patients?
Cohort (n=693)
Are right frontal acute infarcts associated with the development of poststroke anxiety symptoms in stroke patients?
Right frontal acute infarcts are independently associated with a significantly increased risk of developing poststroke anxiety symptoms.
Answers are grounded in this paper and cite their sources.
May prompt anxiety screening in right frontal infarct patients; leaves open need for prospective validation before practice change.
BACKGROUND AND PURPOSE: This study examined the association between poststroke anxiety symptoms (PSA) and frontal lobe infarcts. METHODS: A cohort of 693 patients was recruited. PSA was defined as an anxiety subscale of the Hospital Anxiety and Depression Scale score of 8 or above. The presence and location of infarcts were evaluated with MRI. RESULTS: Compared with the non-PSA group, PSA patients were more likely to have right frontal acute infarcts. Right frontal infarcts remained independent predictors of PSA in the multivariate analysis, with an odds ratio of 4.44 (P=0.002). CONCLUSIONS: The results suggest that right frontal acute infarcts may play a role in the development of PSA.
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Tang et al. (2012) conducted a cohort in Stroke (n=693). Right frontal acute infarcts vs. Absence of right frontal acute infarcts was evaluated on Poststroke anxiety symptoms (PSA) (OR 4.44, p=0.002). Right frontal acute infarcts were an independent predictor of poststroke anxiety symptoms.
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