Key result
Subendocardial involvement on cardiac MRI in myocarditis was associated with a significantly higher rate of major adverse cardiovascular events compared to no involvement (83% vs 33%; P=0.002).
Why the study?
Subendocardial late gadolinium enhancement on cardiac MRI in myocarditis presents a diagnostic dilemma because it can resemble myocardial ischemia.
Does subendocardial involvement on cardiac MRI predict worse clinical outcomes in patients with pathologically proven myocarditis?
Population
39 patients with pathologically proven myocarditis
Comparison
Subendocardial involvement vs no subendocardial involvement on cardiac MRI
Design
Retrospective study
Follow-up
Median 784 days
Authors
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Subendocardial involvement on CMR was associated with worse outcomes in proven myocarditis; hypothesis-generating and requires prospective validation before changing practice.
Observational (n=39)
Does subendocardial involvement on cardiac MRI predict worse clinical outcomes in patients with pathologically proven myocarditis?
Absolute Event Rate: 83% vs 33%
p-value: p=.002
Li et al. (2021) conducted an observational in Myocarditis (n=39). Subendocardial involvement at cardiac MRI vs. No subendocardial involvement was evaluated on Major adverse cardiovascular events (MACE) (p=.002). Subendocardial involvement on cardiac MRI in myocarditis was associated with a significantly higher rate of major adverse cardiovascular events compared to no involvement (83% vs 33%; P=0.002).
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