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March 1, 2022PLoS neglected tropical diseasesOpen Access

Factors associated with in-hospital mortality of adult tetanus patients–a multicenter study from Bangladesh

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Authors

MKMd. Abdullah Saeed KhanMHMohammad Jahid HasanMRMd. Utba Rashid

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Overview

Prospective observational study reveals age and onset time as key mortality factors in tetanus patients, suggesting need for targeted care.

Key Points

  • To identify factors associated with in-hospital mortality of adult tetanus patients in Bangladesh.
  • Prospective observational study conducted in two infectious disease hospitals.
  • Conveniently selected adult tetanus patients (≥18 years) for inclusion.
  • Data analyzed using Kaplan Meier survival analysis and Cox regression analysis.
  • In-hospital mortality rate was 34.4% (n = 21) among 61 tetanus cases.
  • Age (≥40 years) and onset time (≤4 days) were significant predictors of in-hospital mortality with aHRs of 4.03 and 3.33 respectively.
  • Complications and incubation period were also considered but did not show significant predictive power.

Cite This Study

Khan et al. (2022) studied this question.

synapsesocial.com/papers/6a6c25e926cff2e2f6f4a038https://doi.org/10.1371/journal.pntd.0010235
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Characteristics and Factors Associated with In-Hospital Mortality Among Adult Tetanus Patients in Bangladesh: A Retrospective Cohort Study2026
  2. 2Mortality and Associated Factors Among Adult Tetanus Patients Admitted at Public Hospitals in Bahir Dar City, Ethiopia: A Cross‐Sectional Study2026
  3. 3Impact of Sociodemographic Variables and Clinical Parameters On Outcome of Pediatric Tetanus Patients: A Retrospective Study From an Infectious Disease Hospital in Bangladesh2025
  4. 4Management and outcome of adult generalized tetanus patients in a tertiary hospital in Anhui, China: a retrospective study2026
  5. 5Management and outcome of adult generalized tetanus in a Chinese tertiary hospital2024 · 1 citations