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March 21, 2026Critical CareOpen Access

10 years trends and hospitalization outcomes of non-neonatal tetanus: a large-scale multicenter retrospective study in China

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Authors

CLChunxin LiuMLMinli LeiJCJingjing Chen

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Overview

Large-scale study assesses hospitalization outcomes in non-neonatal tetanus, indicating a persistent public health challenge.

Key Points

  • This study aims to analyze the trends and hospitalization outcomes of non-neonatal tetanus in Guangdong, China over ten years.
  • Conducted a multicenter, retrospective study across 159 hospitals in Guangdong.
  • Included 2,567 patients with a clinical diagnosis of tetanus from 2011 to 2021.
  • Collected data on demographics, vaccination status, clinical severity, and outcomes.
  • Hospitalizations increased overall, with rising severe cases (Ablett grade III/IV).
  • Seasonal peaks in cases occurred in August–September.
  • Case fatality rates declined significantly from 11.8% in 2012 to 3.5% in 2021.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69be36666e48c4981c675520https://doi.org/10.1186/s13054-026-05931-z
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