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May 30, 2026BMC Infectious DiseasesOpen Access

Clinical characteristics, management, and outcomes of severe tetanus in the intensive care unit

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Authors

BGBin-bin GuFZFeng-feng ZhuDZDi Zou

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Overview

Retrospective observational cohort study reports outcomes of severe tetanus in adults, suggesting strategies to improve prognosis.

Key Points

  • The aim is to analyze the clinical characteristics and treatment outcomes of adult patients with severe tetanus in the ICU.
  • Retrospective observational cohort study conducted in a tertiary infectious disease hospital.
  • Included adult patients with severe tetanus (Ablett grade III or IV) admitted between January 2014 and December 2024.
  • Data were collected on patient demographics, clinical manifestations, treatments, complications, and outcomes.
  • 36 patients included; in-hospital mortality rate was 16.7%.
  • Common complications included pulmonary infections, occurring in 80.6% of patients.
  • 55.6% of patients showed culture results indicating antimicrobial resistance.

Cite This Study

Gu et al. (2026) studied this question.

synapsesocial.com/papers/6a1a7f990307b78509431db4https://doi.org/10.1186/s12879-026-13697-6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical profile and management of tetanus: A scoping review of evidence in the 21st century2026
  2. 2Management and outcome of adult generalized tetanus in a Chinese tertiary hospital2024 · 1 citations
  3. 3Delayed presentation and management approach of autonomic dysfunction associated with severe tetanus2024 · 1 citations
  4. 4Management and outcome of adult generalized tetanus patients in a tertiary hospital in Anhui, China: a retrospective study2026
  5. 5Management of Tetanus Patients in the Intensive Care Unit : A Case Report2024