Key result
In children with Kawasaki disease, CTCA detected coronary artery thrombosis in 71.4% of positive cases compared to 64.3% by echocardiography, indicating both modalities are complementary.
Why the study?
To compare the diagnostic values of transthoracic echocardiography and multi-slice spiral CT coronary angiography for identifying coronary artery thrombosis in children with Kawasaki disease.
How do transthoracic echocardiography and multi-slice spiral CT coronary angiography compare in identifying coronary artery thrombosis in children with Kawasaki disease?
Observational (n=97)
No
How do transthoracic echocardiography and multi-slice spiral CT coronary angiography compare in identifying coronary artery thrombosis in children with Kawasaki disease?
CTCA and ECHO provide complementary diagnostic value for identifying coronary artery thrombosis in children with Kawasaki disease, with ECHO better suited for low-density thrombi and CTCA for distal clots.
Answers are grounded in this paper and cite their sources.
CTCA may complement ECHO for thrombosis detection in pediatric KD; leaves open optimal strategy pending prospective validation.
Aim: To compare the diagnostic values by using transthoracic echocardiography (ECHO) and multi-slice spiral CT coronary angiography (CTCA) for identifying coronary artery thrombosis in children with Kawasaki disease (KD). Methods: Total 97 KD children with coronary artery dilation complications in our hospital from June 2012 to December 2020 were included in the study. CTCA and ECHO were performed after over 1 month of illness. Results: Coronary artery thrombosis was found in 14 out of 97 patients. Among them, 10 were identified as positive by CTCA, 9 were identified as positive by ECHO, and 5 were identified as positive by both CTCA and ECHO. Conclusion: Both CTCA and ECHO can be used to diagnose coronary artery thrombosis. ECHO has advantage in identifying low-density thrombus, and CTCA is better for the clot in distal coronary artery. They can complement each other.
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Xu et al. (2021) conducted an observational in Kawasaki disease with coronary artery dilation (n=97). Multi-slice spiral CT coronary angiography (CTCA) vs. Transthoracic echocardiography (ECHO) was evaluated on Detection of coronary artery thrombosis. In children with Kawasaki disease, CTCA detected coronary artery thrombosis in 71.4% of positive cases compared to 64.3% by echocardiography, indicating both modalities are complementary.
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