Anesthetic Management in Brugada Syndrome

Brugada syndrome is a rare non-structural cardiac pathology associated with syncope and sudden death, which affects the ion channels (Na+) of cardiomyocytes. It has a high prevalence in males, however there are still very few epidemiological studies that certify it. Currently, various studies have documented the relationship to multiple causal mutations (SCN5A gene); Despite all the advances, there are still unresolved questions that keep the investigation on this matter active. Anesthetic management is a matter of great care in brigade syndrome, its risk is directly associated with the degree of systemic absorption of the same and therefore with the plasma concentration reached. The action of local anesthetics lies in an increase in the changes of the electrocardiogram in this condition because they are sodium channel blockers, acting at the level of phase 0 of the action potential.