Evaluation of the Mandibular Incisive Canal by Panoramic Radiography and Cone-Beam Computed Tomography

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Brugada syndrome (n=13). Intervention: Endocardial radiofrequency ablation. Primary outcome: Non-inducibility of ventricular fibrillation and disappearance of Brugada syndrome ECG pattern.

Pablo E Tauber; V. Mansilla; Pedro Brugada; Sara S Sánchez P; Stella M. Honoré; Marcelo V. Elizari; Sergio Chain Molina; FelixA Albano; Ricardo R Corbalán; Federico Figueroa Castellanos; Damian Alzugaray Bioeng

doi:10.15744/2394-6504.4.101

June 1, 2018Journal of Clinical and Experimental Research in CardiologyOpen Access

Evaluation of the Mandibular Incisive Canal by Panoramic Radiography and Cone-Beam Computed Tomography

View Full Paper

Ask AI

Bookmark

Share

Why the study?

Does endocardial radiofrequency ablation suppress VF inducibility and ECG patterns in patients with Brugada syndrome?

Study Design

Type

Observational (n=13)

Multicenter

No

Structured PICO

Does endocardial radiofrequency ablation suppress VF inducibility and ECG patterns in patients with Brugada syndrome?

P

Population

13 symptomatic patients (mean age 38.7 years, 61.5% female) with spontaneous type 1 Brugada syndrome ECG pattern and inducible ventricular fibrillation, followed for a mean of 34.7 to 44.7 months.

I

Intervention

Endocardial bipolar and electro-anatomic mapping followed by radiofrequency ablation (RFA) of the identified endocardial substrate.

O

Outcome

Suppression of VF inducibility and ECG Brugada syndrome pattern.surrogate

Limitations

Small sample size of only 13 patients.
No genetic studies were performed.
None of the patients had a history of sudden cardiac death or documented spontaneous VT/VF.
Epicardial mapping was not performed, leaving the possibility that a portion of the substrate remained.
Only two patients underwent endomyocardial biopsies.

Implication

Endocardial radiofrequency ablation successfully eliminated the Brugada ECG pattern and VF inducibility in a small cohort of highly symptomatic patients.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Tauber et al. (2018) conducted an observational in Brugada syndrome (n=13). Endocardial radiofrequency ablation was evaluated on Non-inducibility of ventricular fibrillation and disappearance of Brugada syndrome ECG pattern.

synapsesocial.com/papers/6a6c2f4226cff2e2f6f4a420 https://doi.org/10.15744/2394-6504.4.101

View Full Paper

Ask AI

Bookmark

Share

Evaluation of the Mandibular Incisive Canal by Panoramic Radiography and Cone-Beam Computed Tomography

Study Design

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Evaluation of the Mandibular Incisive Canal by Panoramic Radiography and Cone-Beam Computed Tomography

Study Design

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading