Key result
Low-dose subcutaneous heparin is unequivocally effective in preventing deep vein thrombosis and significantly reduces fatal postoperative pulmonary embolism and total mortality.
Why the study?
Does prophylaxis with heparin or mechanical methods prevent fatal pulmonary embolism and DVT in high-risk surgical and medical patients?
Population
Patients over 40 years of age undergoing major surgery, younger patients with a history of venous…
Design
Review
Authors
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Supports perioperative heparin prophylaxis; leaves open cost-effectiveness versus LMWH in contemporary cohorts.
Does prophylaxis with heparin or mechanical methods prevent fatal pulmonary embolism and DVT in high-risk surgical and medical patients?
Low-dose heparin and low molecular weight heparins are effective for venous thromboembolism prophylaxis in high-risk surgical and medical patients, significantly reducing fatal pulmonary embolism and mortality.
Kakkar et al. (1990) conducted a review in Venous thromboembolism. Low-dose subcutaneous heparin was evaluated. Low-dose subcutaneous heparin is unequivocally effective in preventing deep vein thrombosis and significantly reduces fatal postoperative pulmonary embolism and total mortality.
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