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July 28, 2026Substance Use & Misuse

Mapping the Evidence on Kratom Use, Health Outcomes, and Policy Gaps in the United States: A Scoping Review

Sara Burgoa Emmanuel Guirguis Ayden Dunn Cheila Llorens Michelle Knecht Gavin Rose Lea Sacca

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Key Points

This review aims to analyze patterns and health outcomes related to kratom use among U.S. adults while identifying regulatory gaps.
Conducted a scoping review using Joanna Briggs Institute methodology and PRISMA-SCR guidelines.
Included studies published between 2015 and 2025 that focused on U.S. adults and kratom use patterns and outcomes.
Performed qualitative content analysis on data extracted from 43 eligible studies.
Most studies identified were cross-sectional, examining motivations such as pain relief and self-treatment of mental health conditions.
Common health outcomes reported included psychological effects, polysubstance use, and physical symptoms like gastrointestinal issues.
Regulatory factors affecting kratom included legal variability and stigma, highlighting the need for coordinated regulation.

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Implication

Scoping review characterizes kratom use and health impacts in U.S. adults, suggesting regulatory improvements.

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Cite This Study

Burgoa et al. (2026) studied this question.

synapsesocial.com/papers/6a6c46c0747664a1aa73bb4b https://doi.org/10.1080/10826084.2026.2697988

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