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July 31, 2026Korean Journal of OphthalmologyOpen Access

Central Macular Thickness, Subfoveal Choroidal Thickness, and Choroidal Vascularity Index After Phacoemulsification: Bromfenac versus Ketorolac

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Authors

JNJun Sung NahKKKyoung Lae KimKNKyeong Ik Na

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Overview

Retrospective cohort study evaluates postoperative outcomes of bromfenac and ketorolac in cataract surgery patients, suggesting dosing impacts.

Key Points

  • To evaluate the effects of bromfenac and ketorolac on choroidal metrics post-cataract surgery, especially the choroidal vascularity index.
  • Retrospective cohort study with 105 eyes undergoing phacoemulsification, divided into ketorolac (47 eyes) and bromfenac (58 eyes) groups.
  • Patients stratified by preoperative and postoperative dosing regimens: Pre-only and Pre+Post.
  • Assessment of central macular thickness, subfoveal choroidal thickness, and choroidal vascularity index at baseline and one month post-surgery.
  • Both groups showed comparable visual improvements and reductions in intraocular pressure post-surgery.
  • CMT and CVI increased significantly from baseline for both treatments; SCT increased significantly only with bromfenac (p=0.003).
  • Bromfenac maintenance therapy led to smaller increases in CVI compared to Pre-only, with ΔCVI Total at 0.3 ± 3.1% vs. 2.1 ± 3.6% (p=0.027) and ΔCVI 1500 at 0.3 ± 3.8% vs. 2.2 ± 4.0% (p=0.044).

Cite This Study

Nah et al. (2026) studied this question.

synapsesocial.com/papers/6a6c46c0747664a1aa73bb97https://doi.org/10.3341/kjo.2026.0037
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-term effects of short-term postoperative bromfenac on macular thickness after phacovitrectomy for idiopathic epiretinal membrane2026
  2. 2Assessment of anti-inflammatory therapy effectiveness in the early postoperative period of cataract surgery2024
  3. 3One-year Clinical Outcome of Topical Bromfenac in Central Serous Chorioretinopathy2024
  4. 4Efficacy of a one-week course of topical bromfenac combined with corticosteroid for prevention of pseudophakic cystoid macular edema (PCME)2026
  5. 5IMPACT OF NEPAFENAC (0.1%) WITH TOPICAL STEROIDS VERSUS TOPICAL STEROIDS ALONE ON CENTRAL MACULAR THICKNESS AND VOLUME CHANGES POST-CATARACT SURGERY: A RANDOMISED CONTROLLED STUDY2024