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July 31, 2026Food Science & NutritionOpen Access

Total Protein and 10‐Hydroxy‐2‐Decenoic Acid Content, In Vitro Bioaccessibility, Antibacterial, and Antidiabetic Properties of Royal Jelly Collected at Different Harvesting Times

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Authors

EWEyuel WelelawABAbera BelayTATadele Alemu

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Overview

Randomized trial evaluates antibacterial and antidiabetic properties of royal jelly, suggesting optimal harvesting timing for health benefits.

Key Points

  • This study evaluates the effects of harvesting time on protein, 10-hydroxy-2-decenoic acid content, and biological activities of royal jelly.
  • Royal jelly was collected at 72 and 144 hours after larval grafting.
  • The protein and 10-hydroxy-2-decenoic acid content were assessed alongside antibacterial and antidiabetic properties.
  • Bioaccessibility was evaluated at gastric and intestinal stages using standard methods.
  • Royal jelly collected at 72 hours had higher protein (12.99%) and 10-hydroxy-2-decenoic acid (3.39%).
  • Maximal inhibition of α-amylase (75.33%) and α-glucosidase (75.93%) occurred at 72 hours (p < 0.05).
  • IC 50 values for α-amylase were 24.70% (72 h) and 33.87% (144 h), while for α-glucosidase they were 2.81% (72 h) and 12.27% (144 h).

Cite This Study

Welelaw et al. (2026) studied this question.

synapsesocial.com/papers/6a6c472e747664a1aa73c1fdhttps://doi.org/10.1002/fsn3.72127
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