Key result
Excessive removal of reactive oxygen and nitrogen species by exogenous antioxidants may perturb vascular homeostasis and lead to vascular pathology.
Why the study?
Excessive reductive environments induced by exogenous antioxidants may disrupt redox balance and lead to vascular pathology by disturbing crucial physiological roles of reactive oxygen and nitrogen species.
Design
Review
Authors
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Excessive antioxidant use may warrant clinical caution in vascular disease; leaves open optimal redox modulation for targeted trials.
Exogenous antioxidants may disrupt vascular homeostasis by excessively removing reactive oxygen and nitrogen species that play crucial physiological roles in the vasculature.
Costa et al. (2020) conducted a review in Vascular homeostasis and oxidative stress. Exogenous antioxidants was evaluated. Excessive removal of reactive oxygen and nitrogen species by exogenous antioxidants may perturb vascular homeostasis and lead to vascular pathology.
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