Key result
Left ventricular involvement is common in ARVC, with Tl-201 uptake defects present in 93% of patients and significantly decreased mitral annular motion compared to normal subjects.
Why the study?
Do Thallium-201 SPECT and echocardiography detect left ventricular involvement in patients with arrhythmogenic right ventricular cardiomyopathy compared to normal subjects?
Cross-Sectional (n=40)
Do Thallium-201 SPECT and echocardiography detect left ventricular involvement in patients with arrhythmogenic right ventricular cardiomyopathy compared to normal subjects?
Left ventricular involvement is highly prevalent (93%) in ARVC patients and can be detected by Tl-201 SPECT and echocardiography even in asymptomatic patients or those with short disease duration.
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LV assessment in ARVC by Tl SPECT and echo remains inconclusive; leaves open standardized detection before clinical adoption.
Lindström et al. (2005) conducted a cross-sectional in Arrhythmogenic right ventricular cardiomyopathy (ARVC) (n=40). Arrhythmogenic right ventricular cardiomyopathy (ARVC) vs. Normal subjects was evaluated on Tl-201 uptake defects in the left ventricular myocardium. Left ventricular involvement is common in ARVC, with Tl-201 uptake defects present in 93% of patients and significantly decreased mitral annular motion compared to normal subjects.
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