Key result
Src family kinases play a central role in mediating platelet activation, thrombus growth, and stability, making them a key target for understanding thrombotic and hemostatic mechanisms.
Design
Review
Authors
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SFKs central to platelet activation; leaves open selective inhibition as antithrombotic strategy pending trials.
This review highlights the fundamental role of Src family kinases in platelet activation and the potential implications of targeting them for thrombosis and hemostasis.
Senis et al. (2014) conducted a review in Platelet activation and thrombosis. Src family kinases (SFKs) was evaluated. Src family kinases play a central role in mediating platelet activation, thrombus growth, and stability, making them a key target for understanding thrombotic and hemostatic mechanisms.
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