Key result
Higher Systemic Immune-Inflammation Index levels were identified as an independent predictor of non-dipper hypertension (OR 1.023).
Why the study?
Non-dipper HT is associated with greater end-organ damage and cardiovascular events than dipper HT, and inflammation contributes to HT pathophysiology, but the relationship between non-dipper HT and the systemic immune-inflammation index was unknown.
Does the systemic immune-inflammation index (SII) predict non-dipper hypertension in patients with hypertension?
Comparison
Non-dipper HT vs dipper HT
Design
Single-center retrospective study
Authors
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SII may support non-dipper hypertension risk stratification; leaves open prospective validation before clinical use.
Observational (n=91)
No
Does the systemic immune-inflammation index (SII) predict non-dipper hypertension in patients with hypertension?
Odds Ratio: 1.023 (95% CI 1.002–1.112)
p-value: p=0.012
The systemic immune-inflammation index is independently associated with the non-dipper hypertension pattern and may serve as an early warning biomarker.
Akyüz et al. (2022) conducted an observational in Hypertension (n=91). Systemic Immune-Inflammation Index (SII) vs. Dipper hypertension was evaluated on Non-dipper hypertension (OR 1.023, 95% CI 1.002-1.112, p=0.012). Higher Systemic Immune-Inflammation Index levels were identified as an independent predictor of non-dipper hypertension (OR 1.023).
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