Key result
Cocaine use by any route is linked to increased risk of acute and chronic cardiovascular diseases.
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Cocaine use has been associated with both acute and chronic cardiovascular diseases. These include acute myocardial infarction, myocardial ischemia (both silent ischemia and ischemia associated with angina), acceleration of the development of atherosclerosis, myocarditis, cardiomyopathy (both dilated and hypertrophic), arrhythmias, hypertension, aortic dissection, and endocarditis. An estimated 25 million Americans have tried cocaine at least once.Cocaine may be administered by smoking, nasal insufflation, or intravenous injection; cardiac events can follow administration by any of these routes. Cocaine is rapidly absorbed through the respiratory tract; smoking cocaine delivers the substance to the circulation within seconds to minutes. After nasal insufflation . . .
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Kloner et al. (2003) conducted a review in Cardiovascular diseases. Cocaine use was evaluated. Cocaine use by any route of administration is associated with multiple acute and chronic cardiovascular diseases, including myocardial infarction, atherosclerosis, and arrhythmias.
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