Key result
The Surgical Apgar Score was significantly predictive of 30-day mortality and major complications (P < .001) but weakly discriminative (c-statistic 0.63) in emergency high-risk abdominal surgery.
Why the study?
Does the Surgical Apgar Score predict 30-day mortality and major complications in adults undergoing emergency high-risk abdominal surgery?
Cohort (n=355)
No
Does the Surgical Apgar Score predict 30-day mortality and major complications in adults undergoing emergency high-risk abdominal surgery?
Effect estimate: c-statistic 0.63
p-value: p=< .001
The Surgical Apgar Score is predictive but weakly discriminative for major complications and death in emergency high-risk abdominal surgery, and cannot be recommended as a standalone prognostic tool.
SAS weakly discriminates 30-day outcomes in emergency high-risk abdominal surgery; leaves open standalone prognostic utility pending external validation.
BACKGROUND: With current literature quoting mortality rates up to 45%, emergency high-risk abdominal surgery has, compared with elective surgery, a significantly greater risk of death and major complications. The Surgical Apgar Score (SAS) is predictive of outcome in elective surgery, but has never been validated exclusively in an emergency setting. METHODS: A consecutive prospective single-center cohort study of 355 adults undergoing emergency high-risk abdominal surgery between June 2013 and May 2014 is presented. The primary outcome measure was 30-day mortality. Secondary outcome measures were postoperative major complications, defined according to the Clavien-Dindo scale as well as the American College of Surgeons' National Surgical Quality Improvement Program guidelines, and intensive care unit admission. The SAS was calculated postoperatively. Cochran-Armitage test for trend was used to evaluate the incidence of both outcomes. Area under the curve was used to demonstrate the scores' discriminatory power. RESULTS: One hundred eighty-one (51.0%) patients developed minor or no complications. The overall incidence of major complications was 32.7% and the overall death rate was 16.3%. Risk of major complications, death, and intensive care unit admission increased significantly with decreasing SAS (P < .001). The score's c-statistics were 0.63. CONCLUSIONS: We have demonstrated the SAS to be significantly predictive but weakly discriminative for major complications and death among adults undergoing emergency high-risk abdominal surgery. Despite its predictive value, the SAS cannot in its current version be recommended as a standalone prognostic tool in an emergency setting.
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Cihoric et al. (2016) conducted a cohort in Emergency high-risk abdominal surgery (n=355). Surgical Apgar Score (SAS) was evaluated on 30-day mortality (c-statistic 0.63, p=< .001). The Surgical Apgar Score was significantly predictive of 30-day mortality and major complications (P < .001) but weakly discriminative (c-statistic 0.63) in emergency high-risk abdominal surgery.
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