Summary Points:• in contact with an adult with smear-positive tuberculosis (TB) are at high risk of being infected themselves and progressing to TB disease. • World Health Organization recommends that such children, if aged under 5 years, should receive preventive treatment once TB disease has been ruled out. • policy is rarely implemented and attempts to do so have had disappointing results. • propose a new approach using a health needs assessment framework, research tools, and a strategy for clinical evaluation. • show how this approach could be applied and evaluated by National TB Control Programs.
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Hill et al. (2011) studied this question.
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