What question did this study set out to answer?

To determine whether pandemic-era declines in mammographic breast cancer screening persisted postpandemic and to quantify disparities across demographic groups.

December 6, 2025Mayo Clinic Proceedings Innovations Quality & OutcomesOpen Access

Retrospective Analysis of Long-term Impact of COVID-19 Pandemic on Mammographic Breast Cancer Screening

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To determine whether pandemic-era declines in mammographic breast cancer screening persisted postpandemic and to quantify disparities across demographic groups.
Retrospective cohort analysis of 239,804 eligible women aged 40–75 years within the Mayo Clinic system between March 1, 2017, and March 31, 2023.
Evaluated annual screening rates across four pandemic phases using mixed-effects Poisson regression and difference-in-differences models.
Screening rates decreased during the early pandemic (IRR = 0.891, P < .001) and remained significantly below prepandemic levels during the mid-pandemic (IRR = 0.941, P < .001) and late pandemic (IRR = 0.922, P < .001).
Screening was significantly lower among rural versus urban residents (IRR = 0.914, P < .001) and lowest among Black women compared with White women (IRR = 0.692, P < .001).
Difference-in-differences analysis revealed that the relative gap in screening rates for rural and racial minority populations did not significantly widen or narrow over time.

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Implication

Retrospective study observes sustained declines in breast cancer screening through 2023, indicating ongoing disruption without widening disparities.

Cite This Study

Karam et al. (2025) studied this question.

synapsesocial.com/papers/6a6c893c5671bbf00bc2832e https://doi.org/10.1016/j.mayocpiqo.2025.100680

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Implication

Retrospective study observes sustained declines in breast cancer screening through 2023, indicating ongoing disruption without widening disparities.

Retrospective Analysis of Long-term Impact of COVID-19 Pandemic on Mammographic Breast Cancer Screening

Key Points

Discussion

Implication

Cite This Study

Retrospective Analysis of Long-term Impact of COVID-19 Pandemic on Mammographic Breast Cancer Screening

Key Points

Discussion

Implication

Cite This Study

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