What question did this study set out to answer?

To assess the effects of periodontal disease treatment on metabolic control and glycated hemoglobin levels in patients with non-insulin-dependent diabetes mellitus.

August 1, 1997Journal of Periodontology

Treatment of Periodontal Disease in Diabetics Reduces Glycated Hemoglobin

View Full Paper

Ask AI

Bookmark

Authors

SGSara G. GrossiEast Carolina University FSFred B. SkrepcinskiIndian Health Service TDThomas DeCaroIndian Health Service

Discussion

Member takes

Implication

Randomized trial demonstrates that periodontal therapy reduces glycated hemoglobin in type 2 diabetes, suggesting that managing oral infections improves metabolic control.

Key Points

To assess the effects of periodontal disease treatment on metabolic control and glycated hemoglobin levels in patients with non-insulin-dependent diabetes mellitus.
Randomized trial including 113 Native American participants (81 females, 32 males) with periodontal disease and non-insulin-dependent diabetes mellitus allocated across 5 treatment groups.
Interventions comprised ultrasonic scaling and curettage combined with systemic doxycycline (100 mg for 2 weeks) plus topical agents (water, 0.12% chlorhexidine, or povidone-iodine), or placebo plus topical agents (chlorhexidine or water).
Assessments of probing depth, clinical attachment level, subgingival Porphyromonas gingivalis, serum glucose, and glycated hemoglobin (HbA1c) were conducted at baseline, 3 months, and 6 months.
All groups achieved clinical and microbiological improvements, with doxycycline-treated arms showing the greatest reductions in probing depth and subgingival Porphyromonas gingivalis compared to controls.
All three systemic doxycycline groups showed significant reductions in mean HbA1c at 3 months (P ≤ 0.04), decreasing by nearly 10% from pretreatment baseline values.

Cite This Study

Grossi et al. (1997) studied this question.

synapsesocial.com/papers/6a6c96fe75498292b70790ae https://doi.org/10.1902/jop.1997.68.8.713

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial demonstrates that periodontal therapy reduces glycated hemoglobin in type 2 diabetes, suggesting that managing oral infections improves metabolic control.

Treatment of Periodontal Disease in Diabetics Reduces Glycated Hemoglobin

Discussion

Member takes

Implication

Key Points

Cite This Study

Treatment of Periodontal Disease in Diabetics Reduces Glycated Hemoglobin

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider