Key result
Age, diabetes, surgery, and peripherally inserted central venous catheters (PICC) were identified as independent risk factors for gastric cancer-associated thrombotic diseases (P < 0.05).
Why the study?
The risk factors for gastric cancer-associated thrombotic diseases in a Han Chinese population needed investigation.
What are the independent risk factors for thrombotic diseases in Han Chinese patients with gastric cancer?
Case-Control (n=333)
What are the independent risk factors for thrombotic diseases in Han Chinese patients with gastric cancer?
p-value: p=<0.05
Age, diabetes, surgery, and PICC are independent risk factors for thrombotic diseases in gastric cancer patients, highlighting potential targets for early detection and prevention.
Highlights potential thrombosis risks in gastric cancer; leaves open causal inference and prospective validation.
The aim of the present work was to investigate the risk factors for gastric cancer‐ (GC‐) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor‐related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment‐related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC ( P < 0.05), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC‐associated thrombotic diseases ( P < 0.05). The present work demonstrates that GC‐associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia.
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Song et al. (2021) conducted a case-control in Gastric cancer-associated thrombotic diseases (n=333). Age, diabetes, surgery, and PICC vs. Absence of these risk factors was evaluated on Gastric cancer-associated thrombotic diseases (p=<0.05). Age, diabetes, surgery, and peripherally inserted central venous catheters (PICC) were identified as independent risk factors for gastric cancer-associated thrombotic diseases (P < 0.05).
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