Key result
A review of modern fixed combination antihypertensive pharmacotherapy highlights the effectiveness and safety of combining amlodipine, indapamide, and perindopril arginine for achieving target blood pressure.
Why the study?
Achievement of target blood pressure levels is one of the main issues in antihypertensive pharmacotherapy.
This review highlights the 2018 European Guidelines for target blood pressure and supports the use of a triple fixed-dose combination of amlodipine, indapamide, and perindopril arginine for effective and safe antihypertensive therapy.
May guide amlodipine-based fixed combinations per 2018 targets; leaves open optimal regimens in diverse high-risk groups.
Achievement of target blood pressure levels is one of the main issues in antihypertensive pharmacotherapy. The article presents updated 2018 European Guidelines recommendations on target blood pressure levels in antihypertensive therapy and combined antihypertensive pharmacotherapy advantages. Modern fixed combinations including those with three active agents are discussed. A review of studies that show effectiveness and safety of long acting dihydropyridine calcium channel blocker amlodipine, thiazid-like diuretic indapamide, and angiotensin-converting enzyme inhibitor perindopril arginine fixed combination is presented
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Mubarakshina et al. (2018) conducted a review in Hypertension. Fixed combination antihypertensive pharmacotherapy (amlodipine, indapamide, perindopril arginine) was evaluated. A review of modern fixed combination antihypertensive pharmacotherapy highlights the effectiveness and safety of combining amlodipine, indapamide, and perindopril arginine for achieving target blood pressure.
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