Key result
Fixed-dose combination tablets containing amlodipine and olmesartan bring together two distinct mechanisms of action, resulting in improved blood pressure control relative to either agent alone.
Why the study?
Does fixed-dose combination of olmesartan and amlodipine improve blood pressure control in patients with essential hypertension?
Population
Patients with essential hypertension
Comparison
Fixed-dose combination of olmesartan and… vs Monotherapy (either class of agent alone)
Design
Review
Authors
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May support amlodipine-olmesartan FDC for hypertension control; should not yet change practice without randomized outcome trials.
Does fixed-dose combination of olmesartan and amlodipine improve blood pressure control in patients with essential hypertension?
Fixed-dose combination therapy with olmesartan and amlodipine offers a complementary approach to improve blood pressure control in patients with essential hypertension.
Suzanne Oparil (2008) conducted a review in Hypertension. Fixed-dose combination of olmesartan and amlodipine was evaluated. Fixed-dose combination tablets containing amlodipine and olmesartan bring together two distinct mechanisms of action, resulting in improved blood pressure control relative to either agent alone.
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