Key result
In porcine thoracic aortas, Young's modulus and ultimate stress were greatest in the circumferential direction and smallest in the axial direction, demonstrating significant mechanical anisotropy.
Population
24 thoracic aortas from adult boars
Design
Preclinical
Authors
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Multi-directional porcine aortic testing refines constitutive models; leaves open human validation and clinical translation.
This preclinical study demonstrates that the porcine thoracic aorta exhibits significant mechanical anisotropy, with the greatest stiffness and strength in the circumferential direction corresponding to fiber orientation.
Chen et al. (2016) studied Normal porcine thoracic aorta (n=24). Multi-directional uniaxial tensile testing vs. Different sample orientations (e.g., axial vs circumferential) was evaluated on Young's modulus, ultimate stress, and relaxation anisotropy. In porcine thoracic aortas, Young's modulus and ultimate stress were greatest in the circumferential direction and smallest in the axial direction, demonstrating significant mechanical anisotropy.
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